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Neutralization of the oncogenicity of moloney sarcoma virus and moloney leukemia virus by anti-gross serum

✍ Scribed by A. Fefer; J. L. McCoy; J. P. Glynn


Publisher
John Wiley and Sons
Year
1967
Tongue
French
Weight
321 KB
Volume
2
Category
Article
ISSN
0020-7136

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✦ Synopsis


A potent and specific rat anti-Gross serum eflectively neutralized the oncogenicity of Moloney Sarcoma Virus ( M S V ) and Moloney Leukemia Virus ( M L V ) of BALBIc origin. It also reacted against a BALBIc Moloney leukemia but not against a mineral oil-induced BALBIc plasmacytoma by the indirect fluorescent antibody test. The results suggest that either Gross virus has some antigens in common with both MSV and M L V, or that Gross virus shares antigens with MLV which, in turn, determines the virion coat antigens of M S V.


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