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NEUTRALISATION OF ACTION OF HEPARIN BY PROTAMINE

✍ Scribed by Jorpes, Erik; Thaning, Torsten

Book ID
122906479
Publisher
The Lancet
Year
1939
Tongue
English
Weight
352 KB
Volume
234
Category
Article
ISSN
0140-6736

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Protamine sulphate is an effective inhibitor of heparin and is used clinically to neutralise both low molecular weight heparins (LMWH) and unfractionated heparin (UFH). However, protamine sulphate does not fully counter the anti-Xa effect of LMWH, even in excess (>40 ΞΌg to 1 IU/ml). To investigate t

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