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Protamine neutralisation of low molecular weight heparins and their oligosaccharide components

โœ Scribed by Mette Schroeder; John Hogwood; Elaine Gray; Barbara Mulloy; Anne-Marie Hackett; Kristian B. Johansen


Book ID
105893722
Publisher
Springer
Year
2010
Tongue
English
Weight
259 KB
Volume
399
Category
Article
ISSN
1618-2650

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๐Ÿ“œ SIMILAR VOLUMES


Protamine neutralisation of low molecula
โœ Mette Schroeder; John Hogwood; Elaine Gray; Barbara Mulloy; Anne-Marie Hackett; ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Springer ๐ŸŒ English โš– 259 KB

Protamine sulphate is an effective inhibitor of heparin and is used clinically to neutralise both low molecular weight heparins (LMWH) and unfractionated heparin (UFH). However, protamine sulphate does not fully counter the anti-Xa effect of LMWH, even in excess (>40 ฮผg to 1 IU/ml). To investigate t

Determination of Low-Molecular-Weight He
โœ Narayanan Ramamurthy; Narayan Baliga; Thomas W. Wakefield; Philip C. Andrews; Vi ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 95 KB

A polycation-sensitive membrane electrode based on the ion-exchanger dinonylnaphthalene sulfonate has previously been developed and used as an endpoint detector for the determination of unfractionated heparin in whole blood samples via simple potentiometric titration with protamine. Herein, we repor

Oligosaccharide Composition of Heparin a
โœ U.R. Desai; H.M. Wang; S.A. Ampofo; R.J. Linhardt ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 603 KB

The application of capillary electrophoresis to total compositional analysis of heparin and low-molecularweight heparin samples has been studied. Optimum resolution of 17 defined oligosaccharides was obtained with the buffer system composed of \(10 \mathrm{~mm}\) sodium borate and \(50 \mathrm{~mm}\