Vincristine is a chemotherapeutic agent used in the treatment of various neoplastic diseases. Its neurotoxicity after therapeutic and pharmacologic doses has been well documented. We report a case of accidental intrathecal administration of vincristine in order to describe the complications seen, di
Neurourologic consequences of accidental intrathecal vincristine: A case report
โ Scribed by Zaragoza, Michael R. ;Ritchey, Michael L. ;Walter, Andrew
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 204 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0098-1532
No coin nor oath required. For personal study only.
โฆ Synopsis
Inadvertent intrathecal administration of vincristine results in severe neurotoxicity. Motor and sensory bladder dysfunction have been reported but the long-term urologic consequences are unknown due to the associated high mortality. We report a case of accidental intrathecal vincristine adminis-findings. o ~~~i ~e y -~i s s ,
Inc.
tration with patient survival and follow-up of 24 months. The child developed a lower motor neuron neuropathic bladder requiring intermittent self-catheterization of the bladder. Urinary tract management of these children should be based on the urodynamic
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