Inadvertent intrathecal administration of vincristine results in severe neurotoxicity. Motor and sensory bladder dysfunction have been reported but the long-term urologic consequences are unknown due to the associated high mortality. We report a case of accidental intrathecal vincristine adminis-fin
Accidental intrathecal administration of vincristine
โ Scribed by Shepherd, Dell A. ;Steuber, C. Philip ;Starling, Kenneth A. ;Fernbach, Donald J.
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 254 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0098-1532
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โฆ Synopsis
Vincristine is a chemotherapeutic agent used in the treatment of various neoplastic diseases. Its neurotoxicity after therapeutic and pharmacologic doses has been well documented. We report a case of accidental intrathecal administration of vincristine in order to describe the complications seen, discuss possible means of therapeutic intervention, and serve as a reminder that preventive measures are mandatory to avoid such accidents in the future.
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