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Neurotoxicity of monomer mutant SOD1 in Drosophila model of amyotrophic lateral sclerosis

✍ Scribed by Tomohiro Kabuta

Book ID
116778489
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
44 KB
Volume
71
Category
Article
ISSN
0168-0102

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## Abstract Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease. It has been generally accepted that the proapoptotic property of the familial ALS (FALS)‐linked mutant __SOD1__ genes plays an important role in the pathogenesis of some FALS cases. We found here that exp