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Reduced protein O-glycosylation in the nervous system of the mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis

✍ Scribed by Xiaoyang Shan; David J. Vocadlo; Charles Krieger

Book ID
116774107
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
819 KB
Volume
516
Category
Article
ISSN
0304-3940

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## Abstract ## Background and Objective Familial amyotrophic lateral sclerosis (FALS) is a neurodegenerative disease characterized by progressive loss of motor neurons and death. Mitochondrial dysfunction and oxidative stress play an important role in motor neuron loss in ALS. Light therapy (LT) h