Neurotoxicity of gadolinium contrast age
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Masaya Takahashi; Hirokazu Tsutsui; Chie Murayama; Tomoaki Miyazawa; Bernhard Fr
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Article
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1996
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Elsevier Science
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English
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The neurotoxicity of intravenously injected Gadolinium (Gd) complexes to rats with disrupted blood-brain barrier (BBB) was evaluated. After disruption of the BBB by infusion of mannitol solution, one of several contrast agents tested was injected intravenously at a dose of 1 or 3 mmol Gd/kg, and neu