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High-Resolution Functional Magnetic Resonance Imaging of the Rat Brain: Mapping Changes in Cerebral Blood Volume Using Iron Oxide Contrast Media

✍ Scribed by van Bruggen, Nicholas; Busch, Elmar; Palmer, James T.; Williams, Simon-Peter; de Crespigny, Alexander J.


Book ID
110078929
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
774 KB
Volume
18
Category
Article
ISSN
0271-678X

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Regional brain activation by bicuculline
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Functional magnetic resonance imaging (fMRI) has been applied to study rat focal brain activation induced by intravenous administration of the GABA(A) antagonist bicuculline. Using magnetite nanoparticles as a blood pool contrast agent, local changes in cerebral blood volume (CBV) were assessed with