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Neurotensin stimulates PKC-dependent and EGFR-independent ERK activation in human pancreatic cancer

✍ Scribed by Guha, Sushovan; Santiskulvong, Chintda; Rozengurt, Enrique


Book ID
122922674
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
271 KB
Volume
124
Category
Article
ISSN
0016-5085

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✍ Xian-Zhong Ding; Wei-Gang Tong; Thomas E. Adrian πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 203 KB

We previously reported that inhibition of the 12-lipoxygenase pathway abolished proliferation and induced apoptosis in several pancreatic cancer cell lines. Furthermore, the 12lipoxygenase product 12(S)-HETE stimulated pancreatic cancer cell proliferation and reversed 12-lipoxygenase inhibitorinduce