## Abstract ## BACKGROUND It was recently shown that neuropilinβ1 (NRPβ1), which was described originally as a receptor for the semaphorins/collapsins (ligands involved in neuronal guidance), is a coreceptor for vascular endothelial growth factor (VEGF) and increases the affinity of specific isofo
β¦ LIBER β¦
Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer
β Scribed by Min Li; Yuqing Zhang; Louis W. Feurino; Hao Wang; William E. Fisher; F. Charles Brunicardi; Changyi Chen; Qizhi Yao
- Book ID
- 108584136
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 213 KB
- Volume
- 99
- Category
- Article
- ISSN
- 1347-9032
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Vascular endothelial growth factor (VEGF) is a potent angiogenic polypeptide that activates 2 distinct high-affinity tyrosine kinase receptors, flk-1/KDR and flt-1. In the present study, we characterized the expression of VEGF and its receptors flk-1/KDR and flt-1 in the normal human pancreas and in