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Neurotensin-SPDP-poly-l-lysine conjugate: a nonviral vector for targeted gene delivery to neural cells

✍ Scribed by Daniel Martinez-Fong; Iván Navarro-Quiroga; Ivonne Ochoa; Ikuri Alvarez-Maya; Marco Antonio Meraz; José Luna; José-Antonio Arias-Montaño

Book ID: 117387331
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 962 KB
Volume: 69
Category: Article
ISSN: 0169-328X
DOI: 10.1016/s0169-328x(99)00114-x

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## Abstract An efficient endosome‐escaping function was integrated into the polyplex of plasmid DNA (pDNA) with poly(L‐lysine) (PLys) to improve its gene transfection efficiency through electrostatic coating with charge‐conversional polymer (CCP). CCP showed charge‐conversional function responding