## Abstract Dopaminergic damage inducing Parkinson's disease (PD) is ubiquitous neurodegenerative disorder, characterized by the progressive loss of dopaminergic neurons in the nigrostriatal pathways. The etiology and pathogenic factors implicated in dopaminergic damage are still unexplored to deve
β¦ LIBER β¦
Neuroprotective or Neurotoxic Activity of 1-Methyl-1,2,3,4-tetrahydroisoquinoline and Related Compounds
β Scribed by Katsuhiro Okuda; Yaichiro Kotake; Shigeru Ohta
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 107 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The synthesis of 3βmethylβ and 3,4βdimethyltetrahydroisoquinolines from aromatic aminoalkenes using intramolecular hydroamination reactions is described. This reaction was achieved by way of a reductive aminomercuration using mercuric acetate followed by sodium borohydride, or by using