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Neuroprotective mechanisms of peroxisome proliferator-activated receptor agonists in Alzheimer’s disease

✍ Scribed by Rupinder K. Sodhi; Nirmal Singh; Amteshwar S. Jaggi

Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
313 KB
Volume
384
Category
Article
ISSN
0028-1298

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## Abstract Peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) plays a critical role in glucose and lipid metabolism. More recently, PPAR‐γ ligands have been reported to inhibit the expression of proinflammatory molecules by monocytes/macrophages. Of relevance to CNS disease is that PPAR‐γ agoni