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Neuroprotective effects of umbelliferone and esculetin in a mouse model of Parkinson's disease

✍ Scribed by Subramaniam, Sudhakar R.; Ellis, Elizabeth M.


Book ID
118763174
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
980 KB
Volume
91
Category
Article
ISSN
0360-4012

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This is the first study to investigate the potential protective effects of the lipophilic kavapyrone (+/-)-kavain in the experimental MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) model of Parkinson's disease (PD). Male C57BL/6 mice were treated with (+/-)-kavain (50, 100, or 200 mg/kg i.p.) o