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Neuroprotective effects of madecassoside in early stage of Parkinson's disease induced by MPTP in rats

โœ Scribed by Xu, Chang-Liang; Qu, Rong; Zhang, Jin; Li, Lu-Fan; Ma, Shi-Ping

Book ID
121217812
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
707 KB
Volume
90
Category
Article
ISSN
0367-326X

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This is the first study to investigate the potential protective effects of the lipophilic kavapyrone (+/-)-kavain in the experimental MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) model of Parkinson's disease (PD). Male C57BL/6 mice were treated with (+/-)-kavain (50, 100, or 200 mg/kg i.p.) o