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Neuroprotective effects of coadministration of HB-GAM and GDNF in a rat model of Parkinson's disease

✍ Scribed by Marjo Piltonen; Dagmar Ervasti; Heikki Rauvala; Mart Saarma; Pekka T Männistö


Book ID
113591951
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
56 KB
Volume
34
Category
Article
ISSN
0928-0987

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to possess potent neurotrophic effects on dopaminergic (DA) neurons. We attempted the transplantation of encapsulated GDNF‐producing cells to generate a stable supply of GDNF in the brain to promote neuroprotective and re