Neuroprotective and neurorestorative strategies for Parkinson's disease
β Scribed by Dawson, Ted M.; Dawson, Valina L.
- Book ID
- 109941292
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 445 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1097-6256
- DOI
- 10.1038/nn941
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In the context of degenerative disorders of the basal ganglia, neuroprotective therapy refers to interventions that preserve the integrity and function of vulnerable neurons and thereby slow or halt clinical decline. Decoppering therapy for Wilson's disease is the only established neuroprotective th
## Abstract ## Background: Glial cellβderived neurotrophic factor is a survival factor for dopaminergic neurons and a promising candidate for the treatment of Parkinson's disease. However, the delivery issue of the protein to the brain still remains unsolved. Our aim was to investigate the effect