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Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells

✍ Scribed by Francisco Molina-Holgado; Alessandra Gaeta; Paul T. Francis; Robert J. Williams; Robert C. Hider

Book ID
111180825
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
1001 KB
Volume
105
Category
Article
ISSN
0022-3042

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## Abstract The light chain (LC) of botulinum neurotoxin B (BoNT/B) is unable to enter target neuronal cells by itself. It is brought into the cell in association with the BoNT/B heavy chain (HC) through endocytosis. The BoNT HC‐LC subunits are held together by a single disulfide bond. Intracellula