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Neuroprotective actions of aminoguanidine involve reduced the activation of calpain and caspase-3 in a rat model of stroke

✍ Scribed by Ming Sun; Yumei Zhao; Yi Gu; Chao Xu

Book ID
116765434
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
586 KB
Volume
56
Category
Article
ISSN
0197-0186

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## Abstract 6‐Hydroxydopamine (6‐OHDA), a neurotoxin that causes the death of dopamine (DA) neurons, is commonly used to produce experimental models of Parkinson's disease (PD) in rodents. In the rat model of PD first described by Sauer and Oertel, DA neurons progressively die over several weeks fo