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Activation of Calpain, Cathepsin-b and Caspase-3 during Transient Focal Cerebral Ischemia in Rat Model

✍ Scribed by Ganta Vijay Chaitanya; Phanithi Prakash Babu

Publisher
Springer
Year
2008
Tongue
English
Weight
637 KB
Volume
33
Category
Article
ISSN
0364-3190

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## Abstract We have previously reported that prostaglandin A~1~ (PGA~1~) reduces infarct size in rodent models of focal ischemia. This study seeks to elucidate the possible molecular mechanisms underlying PGA~1~'s neuroprotective effects against ischemic injury. Rats were subjected to permanent mid