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Neurophysiological effects of botulinum toxin type a

โœ Scribed by G. Abbruzzese; A. Berardelli

Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
806 KB
Volume
9
Category
Article
ISSN
1029-8428

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## Abstract In some patients, therapy with botulinum toxin type A (BTโ€A) becomes ineffective due to formation of antibodies (BTโ€Aโ€AB). The time course of BTโ€Aโ€AB titres after cessation of BTโ€A therapy was quantitatively studied to determine whether and when they might drop. Thirteen patients (eight

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No convincing evidence exists that botulinum toxin type A (BT-A) injected intramuscularly at therapeutic doses in humans acts directly on central nervous system (CNS) structures. Nevertheless, several studies, using various approaches, strongly suggest that BT-A affects the functional organization o