Neurophysiologic abnormalities in children with Charcot-Marie-Tooth disease type 1A
✍ Scribed by Eppie M. Yiu; Joshua Burns; Monique M. Ryan; Robert A. Ouvrier
- Book ID
- 109116257
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 192 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1085-9489
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Two sisters with a Charcot-Marie-Tooth disease type 1A (CMT1A) duplication, who had an unusual CMT1A clinical phenotype, are described. The 63-year-old proband presented with dysesthesia on the inner side of the right leg. Neurological examination revealed a localized sensory disturbance in the lowe
## BACKGROUND. A general predisposition for vincristine-related neuropathy has been observed in persons with a family history of hereditary neuropathies. ## METHODS. In a retrospective case series, we investigated the possible association between the DNA rearrangement found in patients with Cha