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Neuropharmacological assessment of potential dopamine D4 receptor-selective radioligands

✍ Scribed by Nora S. Kula; Frank I. Tarazi; Ross J. Baldessarini; Lixiao Xu; Venkatesalu Bakthavachalam; Scott Pounds; C.Diane True


Book ID
114016964
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
70 KB
Volume
367
Category
Article
ISSN
0014-2999

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The identification of a novel dopamine receptor subtype, referred to as the D4 receptor, which binds the atypical antipsychotic drug clozapine with high potency, has led to the initiation of a drug discovery program that aims to find novel inhibitors of this receptor subtype. A selective screening s