## Abstract __Clock__ is a member of a highly conserved transcription control network that underlies the circadian cycle. During early embryogenesis, its expression is developmentally regulated and may be required for the normal development of the head. In this report, the transcription factor __Pa
Neuromedin-U is regulated by the circadian clock in the SCN of the mouse
โ Scribed by E. Scott Graham; Pauline Littlewood; Yvonne Turnbull; Julian G. Mercer; Peter J. Morgan; Perry Barrett
- Book ID
- 109023803
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 300 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0953-816X
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## Abstract Many biochemical, physiological, and behavioral processes in organisms ranging from prokaryotes to humans exhibit circadian rhythms, defined as cyclic oscillations of about 24 hours. The mechanism of the cellular circadian clock relies on interlocking positive and negative transcription
The expression of dbp, a putative clock-controlled transcription factor, was investigated in the mouse brain by in situ hybridization using antisense cRNA probe. Positive dbp mRNA signals were detected in various parts of the brain, with the highest expression in the suprachiasmatic nucleus (SCN). T