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Pax6 is a direct, positively regulated target of the circadian gene Clock

✍ Scribed by Richard Morgan

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 453 KB
Volume: 230
Category: Article
ISSN: 1058-8388
DOI: 10.1002/dvdy.20097

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✦ Synopsis

Abstract

Clock is a member of a highly conserved transcription control network that underlies the circadian cycle. During early embryogenesis, its expression is developmentally regulated and may be required for the normal development of the head. In this report, the transcription factor Pax6, a highly conserved regulator of anterior development, is shown to be a direct target of Clock regulation. Developmental Dynamics 230:643–650, 2004. © 2004 Wiley‐Liss, Inc.

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