Role of sensory neurons in colitis: incr
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Matthias A. Engel; Christoph Becker; Peter W. Reeh; Markus F. Neurath
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Article
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2011
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John Wiley and Sons
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English
⚖ 112 KB
Growing evidence suggests a crucial involvement of extrinsic sensory neurons in the aberrant immune response in colitis. Activation of sensory neurons is accompanied by a release of the neuropeptides calcitonin gene-related peptide (CGRP) and substance P (SP), which induce neurogenic inflammation ch