Neurofilament Phosphorylation in Peripheral Nerve: Changes with Axonal Length and Growth State

Anomalous phosphorylated neurofilament a

Anomalous phosphorylated neurofilament aggregations in central and peripheral axons of hens treated with tri-Ortho-cresyl phosphate (TOCP)

✍ K. F. Jensen; D. M. Lapadula; J. Knoth Anderson; N. Haykal-Coates; Dr. M. B. Abo 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 949 KB

Previous biochemical studies demonstrated a dramatic increase in phosphorylation of cytoskeletal proteins that occurs early in organophosphorus esterinduced delayed neurotoxicity (OPIDN). In this report we present immunohistochemical evidence that there is anomalous aggregation of phosphorylated neu