Neurofilament L gene is not a genetic factor of sporadic and familial Parkinson’s disease
✍ Scribed by Nils Rahner; Carsten Holzmann; Rejko Krüger; Ludger Schöls; Klaus Berger; Olaf Riess
- Book ID
- 113998397
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 121 KB
- Volume
- 951
- Category
- Article
- ISSN
- 0006-8993
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Recent interest has focused on the largest pedigree reported to date with histologically proven Lewy body parkinsonism with an autosomal-dominant mode of transmission.' It consisted of descendants of several immigrants to the United States linked to collateral Italian descendants by a common ancesto
## Abstract ## __Objective__ The __UCHL‐1__ gene is widely cited as a susceptibility factor for sporadic Parkinson's disease (PD). The strongest evidence comes from a meta‐analysis of small studies that reported the S18Y polymorphism as protective against PD, after pooling studies of white and Asi