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Neurofibromatosis type 1 is a genetic skeletal disorder

✍ Scribed by David A. Stevenson; David H. Viskochil; John C. Carey

Book ID
101451227
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
66 KB
Volume
143A
Category
Article
ISSN
1552-4825

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## Abstract **BACKGROUND**: The disorder neurofibromatosis type 1 (NF1) is caused by mutations in the __NF1__ gene, which influences the availability of activated Ras and the latter's control of cellular proliferation. Emphasis on this aspect of __NF1__ has focused attention on the tumor suppressio