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The Neurofibromatosis type 1:A dominantly inherited tumors-predisposing disorder

✍ Scribed by Scalzone, Maria ;Coccia, Paola ;Ruggiero, Antonio ;Lazzareschi, Ilaria ;Mastrangelo, Stefano ;Riccardi, Riccardo

Book ID
111489905
Publisher
Walter de Gruyter GmbH
Year
2009
Tongue
English
Weight
795 KB
Volume
4
Category
Article
ISSN
2391-5463

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## Abstract **BACKGROUND**: The disorder neurofibromatosis type 1 (NF1) is caused by mutations in the __NF1__ gene, which influences the availability of activated Ras and the latter's control of cellular proliferation. Emphasis on this aspect of __NF1__ has focused attention on the tumor suppressio