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Neurofibromatosis type 1 gene mutations in neuroblastoma

โœ Scribed by The, Inge; Murthy, Anita E.; Hannigan, Gregory E.; Jacoby, Lee B.; Menon, Anil G.; Gusella, James F.; Bernards, Andre


Book ID
109914892
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
669 KB
Volume
3
Category
Article
ISSN
1061-4036

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Neurofibromatosis type 1 ("1) is one of the most common inherited disorders, with an incidence of 1 in 3,000. We screened a total of 320 unrelated NF1 patients for mutations in exon 37 of the NF1 gene. Six independent mutations were identified, of which three are novel, and these include a recurrent