Neurofibrillary tangles and neuritic plaques in cognitively impaired nondemented and in cognitively normal elderly individuals: Evidence for early Alzheimer's disease
โ Scribed by Renata Leite; Mariana Molina; Lea Grinberg; Claudia Suemoto; Renata Ferretti; Jose Farfel; Edilaine Tampellini; Ana Alho; Carlos Pasqualucci; Wilson Jacob-Filho; Ricardo Nitrini
- Book ID
- 118468724
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 86 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1552-5260
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๐ SIMILAR VOLUMES
## Abstract ## Objective The possibility of brain volume reserve effects was examined in a sample of geriatric outpatients with mild cognitive impairment (MCI), Alzheimer's disease (AD) and vascular dementia (VaD). The total intracranial volume (ICV) served as an estimate of the maximum attained b
Recent studies indicate that there is a marked reduction in trkA-containing nucleus basalis neurons in end-stage Alzheimer's disease (AD). We used unbiased stereological counting procedures to determine whether these changes extend to individuals with mild cognitive impairment (MCI) without dementia