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Neuroendocrine differentiation is involved in chemoresistance induced by EGF in prostate cancer cells

โœ Scribed by Yuan Li; He Qun Chen; Min Feng Chen; Huai Zheng Liu; Yuan Qing Dai; Hui Lv; Xiong Bing Zu; Lin Qi

Book ID
116719587
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
664 KB
Volume
84
Category
Article
ISSN
0024-3205

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โœ Spiotto, Michael T.; Chung, Theodore D.K. ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 653 KB

## Background: In the human prostate cancer cell line lncap, interleukin (il)-6 has been shown to regulate both growth and neuroendocrine (ne) differentiation. we recently observed that il-6 mediated growth arrest in lncap by activating stat 3. since differentiation and growth arrest are often asso