Neurodevelopment, Aging and Cognition

✍ Scribed by Ivica Kostović, Zdravko Petanjek, Ivana Delalle, Miloš Judaš (auth.), Ivica Kostović, Stevo Knežević, Henryk M. Wisniewski, George J. Spilich (eds.)

• Publisher: Birkhäuser Basel
• Year: 1992
• Tongue: English
• Leaves: 403
• Edition: 1
• Category: Library

✦ Synopsis

It was Oscar Wilde who defined the tragedy of old age by saying that " . . . as soon as you are old enough to know better, you don't know anything at all. " As improvements in the quality of health care bring about longer life, our attention has turned from the prolonging of life to the maintenance of involvement in life. In developed nations, a full 100% increase in the ranks of the elderly has appeared and with the benefits of this prolongation have come new and greater needs of the elderly cohort. Our interest is in those processes that may lead to dementia among the elderly, for in dementia we see a thief that robs victims of their memories and their place in life. This text was conceived and developed from an international con­ ference on neurodevelopment, aging, and cognition; the purpose of this few days a group of experts in these conference was to bring together for a fields from around the world to generate a dialog on common themes and unresolved problems. Our hope was that by keeping the meeting small and informal, we could break through barriers of terminology unique to the areas of developmental neurobiology, neuroscience, cognitive sci­ ence, and clinical medicine, and have a meaningful discussion on pro­ cesses that affect the biological integrity and cognitive performance of the aging nervous system.

✦ Table of Contents

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Developmental Reorganization of the Human Association Cortex during Perinatal and Postnatal Life....Pages 3-17
Prenatal Monoaminergic Innervation of the Cerebral Cortex: Differences between Rodents and Primates....Pages 18-36
Ontogenetic Development and Decline of Memory Functions in Nonhuman Primates....Pages 37-59
Anoxia and Memory Processes....Pages 60-74
Brain before Cognition: EEG Maturation in Preterm Infants....Pages 75-98
Mechanisms of Asymmetrical Development of the Human CNS....Pages 99-111
Neuroanatomical Bases of Hemispheric Functional Specialization in the Human Brain: Developmental Factors....Pages 112-137
Front Matter....Pages 139-139
Development and Aging in Down’s Syndrome....Pages 141-156
Alzheimer’s Disease and the Cerebral Amyloidoses....Pages 157-172
Evolution of Cholinergic Cortical Innervation after nbM-Lesioning (An Experimental Alzheimer Model)....Pages 173-198
Neurodegenerative Changes in Aging and Dementia: A Comparison of Alzheimer and Lewy Body Type Pathology....Pages 199-214
Cortical Morphological Changes in Dementia....Pages 215-226
Neuroendocrine Changes in Aging and Alzheimer’s Disease....Pages 227-237
Front Matter....Pages 239-239
Developing a Memory “Thermometer”: A Theoretical Framework and Initial Results....Pages 241-252
Biological Bases of Specific Language Impairment (Developmental Aphasia)....Pages 253-271
Brain/Cognition Relationships: Interpreting the Effects of Focal Brain Damage....Pages 272-291
A Spreading Activation Model of Age-related Deficits in Cognition....Pages 292-303
Memory Changes in Aging....Pages 304-320
Front Matter....Pages 321-321
CT, MRI, and PET Studies of Hippocampal Pathology in Alzheimer’s Disease....Pages 323-335
Is Alzheimer’s Dementia a Treatable Disease?....Pages 336-344
Front Matter....Pages 321-321
Dementia of the Alzheimer Type Recapitulates Ontogeny Inversely on Specific Ordinal and Temporal Parameters....Pages 345-369
Psychopharmacological Aspects of Antidementia Agents....Pages 370-383
Pharmacological Treatment of Alzheimer’s Dementia: A Review....Pages 384-394
Back Matter....Pages 395-396

✦ Subjects

Science, general