𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Neurodegenerative disease: microRNAs under threat from LRRK2

✍ Scribed by Wiedemann, Claudia


Book ID
109963135
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
167 KB
Volume
11
Category
Article
ISSN
1471-0048

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Clinicogenetic study of mutations in LRR
✍ Hiroyuki Tomiyama; Yuanzhe Li; Manabu Funayama; Kazuko Hasegawa; Hiroyo Yoshino; πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 200 KB

We screened LRRK2 mutations in exon 41 in 904 parkin-negative Parkinson's disease (PD) patients (868 probands) from 18 countries across 5 continents. We found three heterozygous missense (novel I2012T, G2019S, and I2020T) mutations in LRRK2 exon 41. We identified 11 (1.3%) among 868 PD probands, inc

Comprehensive sequencing of the LRRK2 ge
✍ Barbara Jasinska-Myga; Jennifer Kachergus; Carles VilariΓ±o-GΓΌell; Christian Wide πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 113 KB

## Abstract The __LRRK2__ gene is a key player in Parkinson's disease (PD), however prevalence and pathogenicity of __LRRK2__ variants remain to be investigated in ethnically diverse populations. Herein, we performed comprehensive sequencing of the __LRRK2__ gene in 92 Tunisian probands with famili

LRRK2 R1628P variant is a risk factor of
✍ Zijuan Zhang; Jean-Marc Burgunder; Xingkai An; Yan Wu; Wenjun Chen; Jinhong Zhan πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 66 KB

## Abstract Mutations in __LRRK2__, the gene that encodes leucine‐rich repeat kinase 2 (LRRK2), are associated with autosomal dominant and sporadic forms of Parkinson's disease (PD) and are the most common genetic causes of PD. Recently, a R1628P variant has been reported as a risk factor for PD in