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Neurochemistry, Neuropathology, and Heredity in SAMP8: A Mouse Model of Senescence

✍ Scribed by Koji Tomobe; Yasuyuki Nomura

Book ID
106484361
Publisher
Springer
Year
2009
Tongue
English
Weight
334 KB
Volume
34
Category
Article
ISSN
0364-3190

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✍ Francisco José Fernández-Gómez; Encarnación Muñoz-Delgado; María Fernanda Monten 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 515 KB

## Abstract The early‐onset, irreversible, severe deficits of learning and memory in the senescence‐accelerated mouse (SAM)‐prone/8 (SAMP8) support its use as an animal model for human dementias of early onset. Possible implication of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) in