Recent studies have shown that delayed transplantation of neural stem/progenitor cells (NSPCs) into the injured spinal cord can promote functional recovery in adult rats. Preclinical studies using nonhuman primates, however, are necessary before NSPCs can be used in clinical trials to treat human pa
Neural transplants in spinal cord injury
โ Scribed by Horvat, J-C
- Book ID
- 109975794
- Publisher
- Nature Publishing Group
- Year
- 1992
- Tongue
- English
- Weight
- 136 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1362-4393
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๐ SIMILAR VOLUMES
Transplantation of neural stem cells (NSCs) has shown promise for improving functional recovery after spinal cord injury (SCI). The inhospitable milieu of injured spinal cord, however, does not support survival of grafted NSCs, reducing therapeutic efficacy of transplantation. The present study soug
## Abstract Transplantation of neural stem cells (NSC) into lesioned spinal cord offers the potential to increase regeneration by replacing lost neurons or oligodendrocytes. The majority of transplanted NSC, however, typically differentiate into astrocytes that may exacerbate glial scar formation.