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Network analysis of icb-1 gene function in human breast cancer cells

✍ Scribed by Oliver Treeck; Derya Belgutay; Julia Häring; Susanne Schüler; Claus Lattrich; Olaf Ortmann

Book ID
112120216
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
474 KB
Volume
113
Category
Article
ISSN
0730-2312

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## Abstract The three mammalian HP1 proteins, HP1α/CBX5, HP1β/CBX1, and HPγ/CBX3, are involved in chromatin packing and gene regulation. The HP1α protein is down‐regulated in invasive compared to non‐invasive breast cancer cells and HP1α is a suppressor of cell migration and invasion. In this repor