For the two dysgerminornas in the study by Marx et al. in which overexpression of p53 was detected by LIO-7 and DO-1 in greater than 50% of the tumor cell nuclei, we suggest a further molecular analysis to verify the presence of p.53 mut a t' ion.
Nerve-sparing radical retropubic prostatectomy for localized prostate cancer. The pros and cons
β Scribed by Philippe E. Zimmern; Gary E. Leach
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 476 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
β¦ Synopsis
Since the precise description of the course of the cavernous nerves dorsolateral to the prostate by Walsh and Donker in 1982, a trend has emerged to offer a "nervesparing" procedure to potent males diagnosed with localized prostate cancer. This detailed review of the literature focuses on the potency results attained by this operation, reviews the shortcomings of this approach in terms of cancer eradication and continence, and attempts to define the optimal candidate for such a procedure. Cancer 1995: 75:1944-8.
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The authors thank Ms. Nebahat Gu Β¨rses and Ms. Sylvia Schno Β¨ger for their expert help in performing the in situ hybridizations.