The authors thank Ms. Nebahat Gu Β¨rses and Ms. Sylvia Schno Β¨ger for their expert help in performing the in situ hybridizations.
Survival after radical retropubic prostatectomy of men and clinically localized high grade carcinoma of the prostate
β Scribed by Ian M. Thompson
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 120 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
β¦ Synopsis
For the two dysgerminornas in the study by Marx et al. in which overexpression of p53 was detected by LIO-7 and DO-1 in greater than 50% of the tumor cell nuclei, we suggest a further molecular analysis to verify the presence of p.53 mut a t' ion.
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## Background: The accumulation of chromogranin a (chr a) and cathepsin d (cath d) gene products may be important in prostate carcinoma progression. this study assessed whether the levels of immunoreactivity for chr a and cath d are better predictors of disease specific survival than conventional p
tomy for clinically localized prostate carcinoma are found to have microscopic disease that is not organ-confined, and a significant portion of these patients will