𝔖 Bobbio Scriptorium
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Nerve growth factors in chick tissues

✍ Scribed by Dr. Ted Ebendal; Kjell-Olof Hedlund; Gunilla Norrgren

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
828 KB
Volume
8
Category
Article
ISSN
0360-4012

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✦ Synopsis

Abstract

Bioassays of factors promoting nerve growth in embryonic ganglia are described. Chick embryo extract evokes fiber outgrowth in both sympathetic and ciliary ganglia explanted into a collagen gel. The response is not suppressed by antibodies directed against mouse nerve growth factor (NGF). Chick embryo extract also supported survival of neurons in both intact and dissociated ganglia. In addition to these non‐NGF activities, preliminary evidence is presented for the release of a NGF‐like factor from cultured iris of the adult chick.

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