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Nerve growth factor mediates hyperalgesia and cachexia in auto-immune arthritis

✍ Scribed by David L. Shelton; Jörg Zeller; Wei-Hsien Ho; Jaume Pons; Arnon Rosenthal

Book ID
116817592
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
425 KB
Volume
116
Category
Article
ISSN
0304-3959

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Intraspinal and behavioral consequences of nerve growth factor-induced nociceptive sprouting and nerve growth factor-induced hyperalgesia compared in adult rats
✍ Pertens, Evi; Urschel-Gysbers, Bethany A.; Holmes, Michael; Pal, Raveen; Foerste 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 454 KB 👁 2 views

Intraspinal and behavioral events were studied in adult rats with nociceptive nerves that were undergoing collateral sprouting into adjacent denervated skin. This sprouting, which is driven by endogenous nerve growth factor (NGF), did not cause hyperalgesia. For comparison, we studied an exogenous N