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Nerve growth factor levels in mouse serum: Variations due to stress

โœ Scribed by J. Lakshmanan


Publisher
Springer
Year
1987
Tongue
English
Weight
947 KB
Volume
12
Category
Article
ISSN
0364-3190

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Developmental changes in nerve growth fa
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In serum, nerve growth factor (NGF) forms a complex with a,-macroglobulin (a2M), which formation inhibits the immunoreactivity between NGF and its antibodies. For measuring the serum level of NGF, it is thus necessary to liberate NGF from the NGF-a2M complex and prevent reformation of such complex.

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## Abstract The nerve growth factor protein (NGF) isolated from mouse submaxillary gland has been shown to be necessary to the development of vertebrate sensory and sympathetic ganglia. Also, wide ranging alterations in the levels of NGF in the peripheral circulation of humans suffering from a vari