Nerve-dependent gene expression in the epidermis of regenerating salamander limbs
โ Scribed by James R. Monaghan; Ashley W. Seifert; Randal Voss; David M. Gardiner; Malcolm Maden
- Book ID
- 116978254
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 54 KB
- Volume
- 344
- Category
- Article
- ISSN
- 0012-1606
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The present study is an analysis of neurotrophic control of DNA and protein synthesis in the separated epidermis and blastema of the early newt limb regenerate. Previous macromolecular studies employed the entire regenerate without discrimination between its two components. The results
Denervation of the amputated limb of newts stops the regeneration process by decreasing blastema cell proliferation. We investigated the effect of the denervation on each of the two compartments (epidermal cap, mesenchyme) in mid-bud blastemas on the level of sulphated glycosaminoglycans (GAGS). Den