Nerve conduction and aldose reductase inhibition during 5 years of diabetes or galactosaemia in dogs
โ Scribed by R. L. Engerman; T. S. Kern; M. E. Larson
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 551 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0012-186X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The effects of orally-administered myo-inositol have been compared with those of an aldose reductase inhibitor on acute neurological defects in experimentally diabetic rats. Three groups of streptozotocin-treated diabetic rats (50 mg/kg, IP) together with three groups of age-matched controls (saline
This study describes reduced motor nerve conduction velocity and increased resistance to hypoxia-induced conduction failure in sciatic nerves of rats after four weeks of streptozotocin-induced diabetes (both effects were significant at p < 0.05). These changes occurred in the absence of any deficit