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Nerve conduction abnormalities in the trembler-j mouse: A model for Charcot-Marie-Tooth disease type 1A?

✍ Scribed by Gregg D. Meekins; Michael J. Emery; Michael D. Weiss


Book ID
110760860
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
212 KB
Volume
9
Category
Article
ISSN
1085-9489

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Peripheral myelin protein-22 (PMP22) is expressed in myelinating Schwann cells and shows significant homology to murine growth arrest-specific gene gas3. Charcot-Marie-Tooth disease type l a (CMTla) is a common hereditary demyelinating neuropathy. Recently it was demonstrated that the gene for PMP22