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Neonatal Fc Receptor: From Immunity to Therapeutics

✍ Scribed by Timothy T. Kuo; Kristi Baker; Masaru Yoshida; Shuo-Wang Qiao; Victoria G. Aveson; Wayne I. Lencer; Richard S. Blumberg

Publisher
Springer
Year
2010
Tongue
English
Weight
233 KB
Volume
30
Category
Article
ISSN
0271-9142

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πŸ“œ SIMILAR VOLUMES

Immunity against a therapeutic xenoprote
Immunity against a therapeutic xenoprotein/Fc construct delivered by gene transfer is reduced through binding to the inhibitory receptor FcΞ³RIIb
✍ Yaming Liang; Hongmin Qiu; Yelena Glinka; Alan H. Lazarus; Heyu Ni; Gerald J. Pr πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 338 KB

## Abstract ## Background Therapeutic xenoproteins are immunogenic and can induce neutralizing antibodies. When delivered by intramuscular injection of a plasmid vector, this mimics classical DNA vaccination. To demonstrate this, we chose Exendin‐4 (Ex4), which is a glucagon‐like peptide‐1 mimetic