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Neonatal BCG vaccination induces IL-10 production by CD4+ CD25+ T cells

✍ Scribed by Tunc Akkoc; Metin Aydogan; Aysegul Yildiz; Elif Karakoc-Aydiner; Aarif Eifan; Sevgi Keles; Mustafa Akin; Sultan Kavuncuoglu; Nerin N. Bahceciler; Isil B. Barlan


Book ID
110895526
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
169 KB
Volume
21
Category
Article
ISSN
0905-6157

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IL-2 induces in vivo suppression by CD4+
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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a