## Abstract TGF‐β and IL‐4 were recently shown to selectively upregulate IL‐9 production by naïve CD4^+^ T cells. We report here that TGF‐β interactions with IL‐1α, IL‐1β, IL‐18, and IL‐33 have equivalent IL‐9‐stimulating activities that function even in IL‐4‐deficient animals. This was observed af
✦ LIBER ✦
DX5+CD4+ T cells modulate cytokine production by CD4+ T cells towards IL-10 via the production of IL-4
✍ Scribed by Wanda G. H. Han; Ellen I. H. van der Voort; Hanane el Bannoudi; Pascale Louis-Plence; Tom W. J. Huizinga; René E. M. Toes
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 474 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0014-2980
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## Abstract IL‐10‐producing regulatory B cells have been identified in mice and shown to downregulate inflammation, making them potentially important for maintenance of tolerance. In this study, we isolated B cells from human blood and spleen, and showed that after a short period of __ex vivo__ sti